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FAQs about VABYSMO

Frequently asked questions

Please note, any and all questions regarding VABYSMO should be discussed with your Retina Specialist. These questions may help you get started with the conversation.


VABYSMO is a prescription medicine administered by injection into the eye by your Retina Specialist.

It is approved for the treatment of wet age-related macular degeneration (wet AMD) and diabetic macular edema (DME).

VABYSMO may cause serious side effects, including:

  • Inflammation and detached retina (separation of the retina from the back of the eye), which have been associated with injections in the eye
  • A temporary increase in eye pressure has been seen in some patients within 1 hour of injection
  • Although not common, there is a risk of stroke, heart attack, or even death due to abnormal conditions in the arteries and the veins

The most common side effect with VABYSMO was blood on the white of the eye (conjunctival hemorrhage). This is not the only possible side effect of VABYSMO.

Contact your Retina Specialist right away if you think you might be experiencing any side effects after an injection.

For people with wet AMD, VABYSMO is given every month for the first 4 months. Afterwards, you may go 1-4 months between injections. Your Retina Specialist will decide what the right schedule is for you.

Everyone is different, but studies show that VABYSMO may improve your vision after just 1 treatment.

Wet AMD and DME are chronic conditions that require long-term care. Your Retina Specialist can tell you more about what to expect from treatment with VABYSMO.

Contact your Retina Specialist right away if you think you might be experiencing any side effects.

You may report side effects to the FDA at (800) FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at (888) 835-2555.

For additional Safety Information, please talk to your Retina Specialist and see the VABYSMO full Prescribing Information.

If you are already on a vascular endothelial growth factor (VEGF) treatment, ask your Retina Specialist if switching to VABYSMO is right for you.

There may be options to help you afford your VABYSMO, no matter what type of health insurance you have. 

There are a number of things you can do that can make a big difference in the life of a loved one with vision loss associated with wet AMD or DME.

What is VABYSMO?

VABYSMO (faricimab-svoa) is a prescription medicine given by injection into the eye, used to treat adults with Neovascular (Wet) Age-related Macular Degeneration (AMD) and Diabetic Macular Edema (DME).

Do not receive VABYSMO if you:

  • have an infection in or around your eye. 
  • have active swelling around your eye that may include pain and redness. 
  • are allergic to VABYSMO or any of the ingredients in VABYSMO.

What is the most important information I should know about VABYSMO?

  • Injections like the one for VABYSMO can cause an eye infection (endophthalmitis) or separation of layers of the retina (retinal detachment). Call your healthcare provider right away if you have increasing eye pain, vision loss, sensitivity to light, or redness in the white of the eye.
  • VABYSMO may cause a temporary increase in pressure in the eye (intraocular pressure), which occurs 60 minutes after the injection. 
  • Although not common, VABYSMO patients have had serious, sometimes fatal, problems related to blood clots, such as heart attacks or strokes (thromboembolic events). In clinical studies for wet AMD during the first year, 7 out of 664 patients treated with VABYSMO reported such an event. In DME studies during the first year, 25 out of 1,262 patients treated with VABYSMO reported such an event.

Before receiving VABYSMO, tell your healthcare provider about all of your medical conditions, including if you:

  • Are pregnant or plan to become pregnant. Based on how VABYSMO interacts with your body, there may be a potential risk to your unborn baby. You should use birth control before your first injection, during your treatment with VABYSMO, and for 3 months after your last dose of VABYSMO. 
  • Are breastfeeding or plan to breastfeed. It is not known if VABYSMO passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you receive VABYSMO.
  • Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What should I avoid while receiving VABYSMO? 

  • Your vision may be impaired after receiving an eye injection or after an eye exam; do not drive or use machinery until your vision has recovered sufficiently.  

What are the most common side effects with VABYSMO?

  • The most common side effect with VABYSMO was blood on the white of the eye (conjunctival hemorrhage).
  • These are not all the possible side effects of VABYSMO. 

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects to Genentech at 1-888-835-2555

Please see the VABYSMO full Prescribing Information for additional Important Safety Information.