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For US Healthcare Professionals

Wet Age-related Macular Degeneration (AMD)

*After 4 or 6 initial monthly eye injections, your doctor will choose a schedule of 1 to 4 months. Dosing may vary.

*After 4 or 6 initial monthly eye injections, your doctor will choose a schedule of 1 to 4 months. Dosing may vary.

Why VABYSMO® might be right for you

Eye chart (graphic)

Improves vision quickly with results maintained in the second year of treatment†

Calendar (graphic)

Delivers a chance for up to 4 months between treatments‡

Two ways (graphic)

VABYSMO is the first and only FDA-approved treatment designed to block 2 causes of DME (VEGF and Ang-2§)

Ask your retina specialist about the benefits of treatment with VABYSMO (vah-BUYS-mo)

†In clinical trials of 1262 people on VABYSMO and 625 people on aflibercept, people gained an average of 6 letters on an eye chart at 1 month for both treatments. On average, people gained 11 letters over 1 year and results with VABYSMO were maintained in the second year of treatment, similar to aflibercept.

‡After 4 or 6 initial monthly eye injections, your doctor will choose a schedule of 1 to 4 months. Dosing may vary.

§The benefit of blocking Ang-2 has not been fully determined.

Ang-2=angiopoietin-2; VEGF=vascular endothelial growth factor.

Discover more

LEARN ABOUT DME
LEARN ABOUT VABYSMO

IMPORTANT SAFETY INFORMATION

What is VABYSMO?

VABYSMO (faricimab-svoa) is a prescription medicine given by injection into the eye used to treat adults with neovascular (wet) age-related macular degeneration (AMD) and diabetic macular edema (DME).

Do not receive VABYSMO if you:

  • Have an infection in or around your eye. 
  • Have active swelling around your eye that may include pain and redness. 
  • Are allergic to VABYSMO or any of the ingredients in VABYSMO.

What is the most important information I should know about VABYSMO?

  • Injections like the one for VABYSMO can cause an eye infection (endophthalmitis) or separation of layers of the retina (retinal detachment). Call your healthcare provider right away if you have increasing eye pain, vision loss, sensitivity to light, or redness in the white of the eye.
  • VABYSMO may cause a temporary increase in pressure in the eye (intraocular pressure), which occurs within 60 minutes after receiving the eye injection.
  • Although not common, VABYSMO patients have had serious, sometimes fatal, problems related to blood clots, such as heart attacks or strokes (thromboembolic events). In clinical studies for wet AMD during the first year, 7 out of 664 patients treated with VABYSMO reported such an event. In clinical studies for DME from baseline to week 100, 64 out of 1,262 patients treated with VABYSMO reported such an event.

Before receiving VABYSMO, tell your healthcare provider about all of your medical conditions, including if you:

  • Are pregnant or plan to become pregnant. Based on how VABYSMO interacts with your body, there may be a potential risk to your unborn baby. You should use birth control before your first injection, during your treatment with VABYSMO, and for 3 months after your last dose of VABYSMO.
  • Are breastfeeding or plan to breastfeed. It is not known if VABYSMO passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you receive VABYSMO.
  • Are taking any medications, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Tell your healthcare provider about every medicine you take.

What should I avoid while receiving VABYSMO? 

  • Your vision may be impaired after receiving an eye injection or after an eye exam. Do not drive or use machinery until your vision has recovered sufficiently.

What are the most common side effects with VABYSMO?

  • The most common side effects with VABYSMO were cataract and blood on the white of the eye (conjunctival hemorrhage).
  • These are not all the possible side effects of VABYSMO.

Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects to Genentech at 1-888-835-2555. 

Please see the VABYSMO full Prescribing Information for additional Important Safety Information.