Welcome to VABYSMO.
If you are one of the many people facing the challenges of vision loss... see the possibilities of improved vision with VABYSMO.
VABYSMO is a prescription medicine approved for... the treatment of people with wet age-related macular degeneration—wet AMD... and diabetic macular edema—DME.
Do not receive VABYSMO if you have certain infections, eye swelling or allergic reactions.
With VABYSMO,... you could go 1-4 months between injections... Your Retina Specialist will evaluate your progress to determine the dosing schedule that’s right for you... Imagine the possibilities with VABYSMO.
Please see important information at the end of this video.
VABYSMO works differently from other treatments. Here’s how:
In wet AMD and DME,... there are 2 types of proteins that may lead to blurred vision and possible vision loss.
These proteins can lead to leakage and swelling of blood vessels in the eye.
These 2 proteins are called VEGF and Ang-2.
Other treatments target VEGF.
But VABYSMO is designed to block both types of proteins… to help reduce abnormal blood vessel swelling, help reduce leaking fluid, and help reduce blood vessel growth.
See the possibilities with VABYSMO.
Ask your Retina Specialist if VABYSMO is right for you.
Let’s look at the clinical studies results of VABYSMO in people with wet AMD and DME.
The safety and effectiveness of VABYSMO... were studied for 1 year in 4 clinical trials versus aflibercept.
On average, people with wet AMD gained 6 letters on an eye chart, similar to aflibercept.
Your next wet AMD treatment could be months away. Your Retina Specialist will determine if you can extend your time between injections.
78% of people with wet AMD were able to extend their treatments to every 3 or 4 months. This may not be the experience for all patients.
On average, people with DME gained 11 letters on an eye chart, similar to aflibercept.
VABYSMO gives you a chance to build up to 4 months between injections for DME. Your Retina Specialist can increase or decrease the time between treatments based on their clinical evaluation.
There are 2 possible dosing schedules for people with DME—every 1, 2, 3, or 4 months after 4 starting doses. Or, every 2 months after 6 starting doses.
Talk to your Retina Specialist about a treatment schedule with VABYSMO that’s right for you.
Indications and Important Safety Information
What is VABYSMO?
VABYSMO (faricimab s-v-o-a) is a prescription medicine given by injection into the eye, used to treat adults with Neovascular (Wet) Age-related Macular Degeneration (AMD) and Diabetic Macular Edema (DME).
Do not receive VABYSMO if you:
- have an infection in or around your eye.
- have active swelling around your eye that may include pain and redness.
- are allergic to VABYSMO or any of the ingredients in VABYSMO.
What is the most important information I should know about VABYSMO?
- Injections like the one for VABYSMO can cause an eye infection (endophthalmitis) or separation of layers of the retina (retinal detachment). Call your healthcare provider right away if you have increasing eye pain, vision loss, sensitivity to light, or redness in the white of the eye.
- VABYSMO may cause a temporary increase in pressure in the eye (intraocular pressure), which occurs 60 minutes after the injection.
- Although not common, VABYSMO patients have had serious, sometimes fatal, problems related to blood clots, such as heart attacks or strokes (thromboembolic events). In clinical studies for wet AMD during the first year, 7 out of 664 patients treated with VABYSMO reported such an event. In DME studies during the first year, 25 out of 1,262 patients treated with VABYSMO reported such an event.
Before receiving VABYSMO, tell your healthcare provider about all of your medical conditions, including if you:
- Are pregnant or plan to become pregnant. Based on how VABYSMO interacts with your body, there may be a potential risk to your unborn baby. You should use birth control before your first injection, during your treatment with VABYSMO, and for 3 months after your last dose of VABYSMO.
- Are breastfeeding or plan to breastfeed. It is not known if VABYSMO passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you receive VABYSMO.
- Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
What should I avoid while receiving VABYSMO?
- Your vision may be impaired after receiving an eye injection or after an eye exam; do not drive or use machinery until your vision has recovered sufficiently.
What are the most common side effects with VABYSMO?
- The most common side effect with VABYSMO was blood on the white of the eye (conjunctival hemorrhage).
- These are not all the possible side effects of VABYSMO.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects to Genentech at 1-888-835-2555.
Please see the VABYSMO full Prescribing Information for additional Important Safety Information.
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