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Learn how VABYSMO may help with wet AMD

VABYSMO® improves vision quickly* and delivers a chance for up to 4 months between treatments

*On average, people gained 5 letters at 1 month after their first treatment and gained and maintained 6  letters over 1 year on an eye chart with VABYSMO, similar to aflibercept 2 mg.
After 4 initial monthly eye injections, your doctor will choose a schedule of 1 to 4 months during your first year of treatment. Dosing may vary.

Verana Health® patient share analysis (Oct-Dec 2024); products approved under separate applications considered individually (data on file).

VABYSMO IMPROVES VISION QUICKLY*

On average, people gained and maintained 6 letters on an eye chart over 1 year with VABYSMO, similar to aflibercept 2 mg.

Even greater results of at least 15 letters were achieved by 20% of people taking VABYSMO, similar to aflibercept 2 mg.

VABYSMO helped people quickly gain some vision back after just 1 treatment§

Over 95% of people maintained their vision improvement
after 1 year with VABYSMO, similar to aflibercept 2 mg

Over 95% of people
maintained their vision improvement

after 1 year with VABYSMO, similar to aflibercept 2 mg

§After their first treatment, people on average gained 5 letters on an eye chart at 1 month with VABYSMO, similar to aflibercept 2 mg.

Maintained is defined as not losing 15 letters or more.

EXPLORE A CHANCE FOR UP TO 4 MONTHS INJECTION-FREE

Although most people from the clinical trials went 3-4 months between injections, this may not be the experience of all people. Your retina specialist may evaluate your disease differently from the methods used in our trials. 

After 4 initial monthly doses to stabilize your vision, your retina specialist may want to scan your eye or give you a vision test. These assessments will help determine if you can extend to 2-, 3-, or 4-month dosing. 

Eye chart (graphic)

Improves vision quickly with results maintained after 1 year of treatment*

Two ways (graphic)

The only treatment thought to block 2 causes of wet AMD#

Calendar (graphic)

Delivers a chance for up to 4 months between treatments, so you can do more of what you love

#VABYSMO is thought to block the VEGF and Ang-2 proteins. The benefit of blocking Ang-2 has yet to be established

DME/Wet AMD New Patient Imagery (Debra & David)

"We can move, we can go, we can travel."
 

Debra & David | VABYSMO patients

Wet AMD Patient Imagery (Harold)

"I am so thankful for VABYSMO. I am getting less than half the shots I was getting before."
 

Harold | VABYSMO patient

Wet AMD Patient Imagery (Caroleve)

"I am living proof that your sight can be saved."
 

Caroleve | VABYSMO patient

Patient experiences may vary. Patients compensated by Genentech.

IMPORTANT SAFETY INFORMATION

What is VABYSMO?

VABYSMO (faricimab-svoa) is a prescription medicine given by injection into the eye used to treat adults with neovascular (wet) age-related macular degeneration (AMD), diabetic macular edema (DME), and macular edema following retinal vein occlusion (RVO).

Do not receive VABYSMO if you:

  • Have an infection in or around your eye. 
  • Have active swelling around your eye that may include pain and redness. 
  • Are allergic to VABYSMO or any of the ingredients in VABYSMO.

What is the most important information I should know about VABYSMO?

  • Injections like the one for VABYSMO can cause an eye infection (endophthalmitis), separation of layers of the retina (retinal detachment), or inflammation in the eye that can lead to vision loss. Call your healthcare provider right away if your eye becomes red, sensitive to light, or you have a change or loss of vision.
  • VABYSMO may cause a temporary increase in pressure in the eye (intraocular pressure), which occurs within 60 minutes after receiving the eye injection.
  • Although not common, VABYSMO patients have had serious, sometimes fatal, problems related to blood clots, such as heart attacks or strokes (thromboembolic events). In clinical studies for wet AMD during the first year, 7 out of 664 patients treated with VABYSMO reported such an event. In clinical studies for DME from baseline to week 100, 64 out of 1,262 patients treated with VABYSMO reported such an event. In clinical studies for RVO during 6 months, 7 out of 641 patients treated with VABYSMO reported such an event.
  • Severe inflammation of vessels in the retina has happened for patients treated with VABYSMO. Call your healthcare provider immediately if you experience a change in vision.

Before receiving VABYSMO, tell your healthcare provider about all of your medical conditions, including if you:

  • Are pregnant or plan to become pregnant. Based on how VABYSMO interacts with your body, there may be a potential risk to your unborn baby. You should use birth control before your first injection, during your treatment with VABYSMO, and for 3 months after your last dose of VABYSMO.
  • Are breastfeeding or plan to breastfeed. It is not known if VABYSMO passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you receive VABYSMO.
  • Are taking any medications, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Tell your healthcare provider about all the medicines you take.

What should I avoid while receiving VABYSMO? 

  • Your vision may be impaired after receiving an eye injection or after an eye exam. Do not drive or use machinery until your vision has recovered sufficiently. 

What are the most common side effects with VABYSMO?

  • The most common side effects with VABYSMO were cataract and blood on the white of the eye (conjunctival hemorrhage).
  • These are not all the possible side effects of VABYSMO.

Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects to Genentech at 1-888-835-2555

Please see the VABYSMO full Prescribing Information for additional Important Safety Information.